Since Craze of the Dead God enhances Poison damage, it works best in Diablo 4 Gold Spiritborn builds focused on Poison stacking and sustain mechanics.

1. Poison Predator Build (Best for Boss Damage)

    Core Skills: Predator's Frenzy + Toxic Talons

    Key Synergies: Converts all direct melee hits into Poisoning over time

    Survivability: Gains sustain through Nourishment and Leeching Strikes

This build is perfect for single-target boss fights since it allows Poison stacks to ramp up over time.

2. Venomous Storm Build (Best for AoE Clearing)

    Core Skills: Nature's Wrath + Spirit Surge

    Key Synergies: Combines Lightning Poison, spreading DoT effects across groups

    Survivability: High mobility and damage reduction from Antivenom

This build is excellent for Nightmare Dungeons, Pits, and Infernal Hordes, allowing you to spread Poison effects rapidly while maintaining sustain.

Final Thoughts

For Spiritborn players looking to maximize Poison-based damage, the Craze of the Dead God gloves are one of the most powerful Diablo 4 Items available. With Varshan admissions Poison conversion, Critical Strike bonuses, and AoE spreading mechanics, these gloves allow players to clear high-end content efficiently while staying alive through Antivenom sustain mechanics.